ARCHE Blog

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Explore in-depth articles on biomedical study designs, drawn from expert content on critical appraisal. Each section below provides a teaser and a link to the full detailed page for easy navigation.

Cross-Sectional Studies

A cross-sectional study examines a population at one specific point in time – like taking a “snapshot” of a group’s health status. These studies measure both exposures and outcomes simultaneously, making them ideal for estimating prevalence but not for proving causation.

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Cohort Studies

A cohort study follows a group of people over time to see how exposures affect outcomes. There are prospective and retrospective types, powerful for establishing temporal sequences but potentially expensive.

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Case-Control Studies

A case-control study identifies people with an outcome (cases) and compares them to those without (controls), looking backward at exposures. Efficient for rare diseases but requires careful control selection.

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Randomized Controlled Trials (RCTs)

An RCT randomly assigns participants to intervention or control groups, considered the gold standard for testing causal effects due to randomization balancing confounders.

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